There are 453K new C. difficile infections (CDI) every year and 83K recurrent infections, yet there are no licensed vaccines against this important nosocomial pathogen. The current pipeline of clinical-stage vaccines consists of two toxin-based candidates and one phase 3 candidate, which is no longer being pursued. Although mathematical studies and computer-simulation models suggest that […]
Part 2: Development of antibacterial drugs targeting specific pathogens The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products. Our first webinar was devoted to more traditional approaches (Tiers A and B), best suited for more broad-spectrum products, […]
At least 2 million Americans a year contract an antibiotic-resistant infection, the Centers for Disease Control and Prevention reports. So, what can the U.S. do to safeguard public health amid the growing threat of these superbugs? Tune in to a live webcast as Dr. Scott Gottlieb, commissioner of the U.S. Food and Drug Administration, announces […]
The AMR Challenge encourages global leaders to make formal commitments that further progress against antimicrobial resistance. Your efforts could contribute to solutions that protect humans, animals, and the environment from this global threat. The first batch of commitments will be unveiled at a United Nations (UN) General Assembly side event on September 25, and will […]
Helping Antibacterial Development to Move Forward - New discovery platforms, novel screens and approaches are vital for the discovery of new antibacterials and for ceasing the dangerous trend of multidrug microbial resistance. Cambridge Healthtech Institute's 5th Annual Antibacterial Discovery and Development track will focus on the general, strategic issues and solutions that would allow new […]