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Apply Here

The third of three funding cycle periods is open for Expression of Interest submissions on April 15, 2023 at 9am ET and closes on May 1, 2023 at 11:59pm ET. Applicants can register in the CARB-X Portal by clicking the button below beginning April 15.

Please click here for technical guidance on the CARB-X Portal. If you need technical assistance, please contact

Expressions of Interest (EOI) for all three themes may be submitted during the following timeframes:

  • October 17 at 09:00 ET to October 31, 2022 at 23:59 ET
  • January 16 at 09:00 ET to January 30, 2023 at 23:59 ET
  • April 15 at 09:00 ET to May 1, 2023 at 23:59 ET

The EOI includes three sections:

Organization Details requests details about the legal structure and size of your organization.

Project/Product Details requests details about your project/product including:

  • Type of product (i.e. therapeutic, preventative or diagnostic)
  • Name of your project
  • Target pathogen(s) and whether your product covers isolates resistant to antibiotics from certain classes
  • Primary indication/clinical indication and any secondary indications/clinical applications
  • Stage of development
  • Intended route of administration
  • For Therapeutics/ Preventatives: Modality, Chemical class, Mechanism of action, Details about the target, Target novelty
  • For Diagnostics: Level of complexity, Result output, Diagnostic technology type, Sample type, Time-to-result, Sensitivity/specificity, Target average sales price

You will be asked to describe your therapeutic/preventative/diagnostic in 5000 characters or fewer:

Your application will be judged on the merits of its scientific content; describe your science with as much data as possible. Please do provide sufficient data to allow a knowledgeable scientist to get a reasonable sense of the therapeutic/preventative/ diagnostic. Do not provide other manuscripts, references, citations or similar. Note that the form can only accept text; you may not enter tables or graphics. Do not include foundational information regarding the significance of antibiotic resistance; this is not necessary, as the reviewers understand this.

Project Costs requests details about how much funding you are requesting from CARB-X.

You will be asked to respond to the following question in 250 characters or fewer: Please describe where you are in your project and where you want to progress to. How much funding do you need from CARB-X to complete this scope of work (in USD)?

Target-product profiles can be found here and minimal acceptable criteria can be found here.