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07.14.2024 | ‘My baby died in my arms’: A mother on the dangers of AMR
THE JOURNAL | The world is facing a health crisis which is as serious as the Covid-19 pandemic and could cause millions of premature deaths, but we’re not doing enough to mitigate the risks, experts have warned.
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07.13.2024 | The superbugs lurking in seas and rivers
BBC | Antimicrobial resistance (AMR) develops when the genetic codes of pathogens, including bacteria present in sewage, mutate to resist medicines designed to control infections. Infections caused by the resulting drug-resistant pathogens, sometimes referred to as "superbugs", are estimated to be directly linked to 1.27 million deaths each year.
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07.12.2024 | Climate change could return us to the pre-antibiotic era
SALON | We are in a race with ever-evolving bacteria — and we are losing. Climate change is making the battle much harder.
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07.11.2024 | Resisting antibiotic-resistant bacteria
OTAGO DAILY TIMES | A surprise discovery of microscopic proportions at the University of Otago may have massive potential when it comes to solving the world’s growing resistance to antibiotics. Antibiotic resistance is when bacteria change to resist antibiotics, making certain bacterial infections difficult to treat.
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07.10.2024 | Why is antimicrobial resistance not getting much attention from biopharma?
BIOSPACE | The creation of antibiotics stands as one of the greatest medical breakthroughs in history, saving hundreds of millions of lives, and now halting the rise of AMR has emerged as a global health imperative. The World Health Organization (WHO) has declared that AMR is one of the top global public health and development threats, with nearly 5 million associated deaths per year.
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07.10.2024 | GRAM, IDDO announce AMR data repository to strengthen research and improve access
CENTRE FOR TROPICAL MEDICINE AND GLOBAL HEALTH | Seeking to strengthen research on antimicrobial resistance (AMR) worldwide, the GRAM Project has joined with the Infectious Diseases Data Observatory (IDDO) to create an Oxford-based repository for AMR data, with the first curated dataset now available.
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07.09.2024 | 70% of antibiotics used not working on patients: Expert
TIMES OF INDIA | Noted intensivists from across the country recently gathered in the city to speak at an international symposium on the increasing need for awareness of antimicrobial resistance (AMR).
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07.08.2024 | AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
UNIVERSITY OF CAMBRIDGE | Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, Cambridge researchers have shown. The team showed that an algorithm could be trained to identify drug-resistant bacteria correctly from microscopy images alone.
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07.08.2024 | Impacts of antimicrobial resistance on cancer care
CENTERS FOR DISEASE CONTROL AND PREVENTION | In the eighth installment of CDC's AMR Exchange webinar series, experts discussed the intersection of antimicrobial resistance and cancer care and the importance of preventing infections in people receiving treatment for cancer.
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07.08.2024 | Superbug that now kills 300,000 people a year evolved rapidly from common bacteria
THE INDEPENDENT | A deadly superbug that causes about 300,000 deaths a year evolved from being a common environmental bacterium and spread rapidly in just over two centuries, according to a new study that could help improve our understanding of immunity against invading bacteria.
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07.05.2024 | Tackling antimicrobial resistance in agribusiness and environment
THE UNIVERSITY OF QUEENSLAND | A new training Centre led by The University of Queensland and headquartered at IMB is partnering with industry to tackle the global crisis of antimicrobial-resistant infections, which affect humans, animals and the environment.
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07.03.2024 | PACCARB recommendations for global action against antimicrobial resistance
INFECTIOUS DISEASE ADVISOR | Members of the 25th Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB) held a public meeting from May 21 to 22, 2024 to vote on recommendations to reduce the global threat of antimicrobial resistance (AMR).
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07.01.2024 | WHO launches effort to boost global diagnostic capacity
CIDRAP | The World Health Organization (WHO) last week launched an effort to strengthen global diagnostic capacity and support access to safe, affordable, and quality-assured diagnostics.
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07.01.2024 | Degradation of cell wall key in the spread of resistance
UMEÅ UNIVERSITY | A study at Umeå University, Sweden, provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
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06.25.2024 | Building evidence for the use of bacteriophages against antimicrobial resistance
THE WORLD HEALTH ORGANIZATION | “My father felt powerless, like life was flowing out of him,” explains his daughter, Lies. At the age of 84, after Pim van Vliet underwent a surgery, he began suffering from a chronic urinary tract infection caused by a multi-drug resistant bacterium, Klebsiella pneumoniae.
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06.20.2024 | Antimicrobial resistance: Why the next government needs to prepare for ‘the coming plague’
KING'S COLLEGE LONDON | Could antimicrobial resistance (AMR) be the incoming government’s next major challenge? AMR is a growing global threat, responsible for one in eight global deaths a year – estimated to kill 50 million people per year by 2050.
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06.14.2024 | WHO releases report on state of development of antibacterials
THE WORLD HEALTH ORGANIZATION | The World Health Organization (WHO) today released its latest report on antibacterial agents, including antibiotics, in clinical and preclinical development worldwide. Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for new, innovative agents for serious infections and to replace those becoming ineffective due to widespread use.
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06.06.2024 | Drug-resistant infections more likely to strike women, says WHO
NATURE | Women might be more likely to develop drug-resistant infections than men — an under-recognized aspect of the growing threat of antimicrobial resistance, according to a global review led by the World Health Organization (WHO). The report finds that more than 70% of countries do not recognize gender inequalities in national plans to tackle drug-resistant infections.
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05.29.2024 | How the pandemic gave power to superbugs
NPR | Antibiotics cannot cure COVID. They don’t help a bit. And yet, new data shows that, during the pandemic, COVID patients were given antibiotics – a lot of antibiotics.
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05.23.2024 | The Lancet Series on antimicrobial resistance: The need for sustainable access to effective antibiotics
THE LANCET | Access to effective antibiotics is essential to every health system in the world, however, antimicrobial resistance (AMR) threatens this backbone of modern medicine and is already leading to deaths and disease which would have once been prevented. This Series highlights that, although AMR can affect anyone throughout the life course, the very young, very old and severely ill are the ones suffering the most.
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05.17.2024 | WHO updates list of drug-resistant bacteria most threatening to human health
THE WORLD HEALTH ORGANIZATION | The World Health Organization (WHO) today released its updated Bacterial Priority Pathogens List (BPPL) 2024, featuring 15 families of antibiotic-resistant bacteria grouped into critical, high and medium categories for prioritization. The list provides guidance on the development of new and necessary treatments to stop the spread of antimicrobial resistance (AMR).
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05.13.2024 | Rise of drug-resistant superbugs could make Covid pandemic look ‘minor’, expert warns
THE GUARDIAN | Common infections will kill millions if drug resistance through misuse of antibiotics is not curbed, says England’s ex-chief medical officer
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04.28.2024 | Climate change risks fuelling antibiotic-resistant ‘superbugs’
FINANCIAL TIMES | Antibiotic-resistant “superbugs” are among the greatest public health threats of our age — and researchers fear that climate change will make them still more dangerous.
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04.24.2024 | FDA approves new treatment for uncomplicated urinary tract infections
U.S. FOOD AND DRUG ADMINISTRATION | Today, the U.S. Food and Drug Administration approved Pivya (pivmecillinam) tablets for the treatment of female adults with uncomplicated urinary tract infections (UTIs) caused by susceptible isolates of Escherichia coli, Proteus mirabilis and Staphylococcus saprophyticus.
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04.19.2024 | New antibiotics were underprescribed for hard-to-treat infections, study finds
STAT | Although U.S. regulators approved several new antibiotics for combating hard-to-treat bacteria during a recent five-year period, hospital doctors instead gave older, generic remedies to more than 40% of patients battling those stubborn pathogens, according to a new analysis.
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03.14.2024 | There is a need for awareness about AMR in Indian hospitals: Experts
BHARAT | Admitting that the antimicrobial resistance (AMR) burden in India is among the highest in the world, the Indian Journal of Medical Research (IJMR) has said that healthcare-acquired infections (HAIs) and lack of awareness about it lead to AMR which is one of the top global public health and development threats.
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03.13.2024 | New E. coli: One of the most problematic AMR bacteria in circulation
GASTROENTEROLOGY & ENDOSCOPY NEWS | A new strain of Escherichia coli has been discovered that is both highly virulent and resistant to some antibiotics.
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03.12.2024 | Study reveals ‘considerable farmer knowledge’ on aspects of antibiotics risk
PHYS ORG | A study published in CABI Agriculture and Bioscience has revealed "considerable farmer knowledge" on different aspects of antibiotics risks—including antimicrobial resistance—associated with their use on livestock in Kenya.
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03.07.2024 | University leads thinking on new information systems to tackle AMR at a national level
UNIVERSITY OF LIVERPOOL | Researchers at the University of Liverpool have worked with partners to set out a vision for protecting the UK public against antimicrobial resistance (AMR).
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03.02.2024 | Strengthening laboratory capacities to combat antimicrobial resistance in Sierra Leone
THE WORLD HEALTH ORGANIZATION | In the ongoing battle against the growing threat of antimicrobial resistant (AMR) pathogens, Sierra Leone's Ministry of Health, with support from the World Health Organization (WHO), has embarked on a series of crucial training initiatives. These efforts aimed to equip healthcare professionals especially laboratory officers with the necessary skills to identify bacterial agents and perform antibiotic susceptibility tests as part of activities to combat the threat of AMR effectively.
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03.01.2024 | CSIRO-funded grant advances breakthrough therapeutics for frontline antibiotic rescue
DOHERTY INSTITUTE | University of Melbourne Dr Stephanie Neville, a molecular microbiologist at the Doherty Institute specialising in antibiotic resistance of bacterial pathogens, has been awarded a $500,000 CUREator grant by Brandon BioCatalyst, in the Minimising Antimicrobial Resistance Stream supported by CSIRO.
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03.01.2024 | AMR Industry Alliance calls for ‘bold, coordinated’ action on antimicrobial resistance
CIDRAP | The AMR Industry Alliance this week issued a "call-to-action" in advance of the United Nations (UN) High-Level Meeting on AMR (antimicrobial resistance) in September.
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02.28.2024 | Continued efforts needed to fight antimicrobial resistance (AMR) in humans and animals
EUROPEAN FOOD SAFETY AUTHORITY | Resistance of Salmonella and Campylobacter bacteria to commonly used antimicrobials continues to be observed frequently in humans and animals, according to a report issued today by the European Food Safety Authority (EFSA) and the European Centre for Disease Prevention and Control (ECDC).
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02.28.2024 | Can we keep up with the resistance?
INFECTIOUS DISEASE SPECIAL EDITION | Antimicrobial resistance (AMR) is a leading cause of death worldwide. In 2019 alone, AMR directly resulted in about 1.27 million deaths, and played a role in almost 5 million deaths. Without intervention, that death toll is expected to rise to about 10 million deaths per year by 2050.
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02.28.2024 | European AMR trends in humans, animals, foods for 2021–2022
FOOD SAFETY MAGAZINE | The European Food Safety Authority (EFSA) and the European Center for Disease Prevention and Control (ECDC) recently published a joint report on antimicrobial resistance (AMR) in zoonotic pathogens from humans, animals, and food in 2021–2022. EFSA and ECDC warn about repeatedly observed resistance to common antibiotics in Salmonella and Campylobacter.
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02.28.2024 | Can non-profits beat antibiotic resistance and soaring drug costs?
NATURE | Effective, affordable antimicrobial drugs aren’t moneymakers, despite being desperately needed. Can non-profit organizations pick up the slack?
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02.27.2024 | Global Leaders Group lays out steps to boost antibiotic development, access
CIDRAP | The Global Leaders Group (GLG) on Antimicrobial Resistance (AMR) last week issued a series of recommendations to address shortfalls in the antibiotic pipeline and boost access to new antibiotics and diagnostics.
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02.23.2024 | New guidance document to bolster AMR surveillance in the Western Pacific
DOHERTY INSTITUTE | In the ongoing battle against the threat of antimicrobial resistance (AMR), the WHO Collaborating Centre for Antimicrobial Resistance at the Doherty Institute, in collaboration with the WHO Regional Office for the Western Pacific (WPRO), has taken a significant step forward by developing a guidance document regarding AMR surveillance.
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02.22.2024 | Report suggests lower antibiotic use in Europe led to less antimicrobial resistance
CIDRAP | A multi-agency report ties a reduction in antimicrobial consumption (AMC) in Europe to a decrease in overall antimicrobial resistance (AMR) in people and farm animals from 2014 to 2021.
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02.19.2024 | Antimicrobial resistance diagnostic markets transforming global healthcare with innovative technologies and trends 2023-2027
BUSINESS WIRE | The healthcare sector is on the cusp of a revolution with the latest advancements in diagnostic technologies geared towards combatting antimicrobial resistance (AMR). This new comprehensive research publication analyzes the burgeoning market and the potential these technologies hold in the fight against one of the most pressing healthcare challenges of our time.
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02.19.2024 | Study highlights high rate of multidrug-resistant urinary tract infections in East Africa
CIDRAP | An analysis of urinary tract infection (UTI) isolates from East African countries found that roughly half were multidrug-resistant (MDR), researchers reported last week in JAC-Antimicrobial Resistance.
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02.15.2024 | Could a single synthetic molecule outsmart a variety of drug-resistant bacteria?
LA TIMES | An estimated 2.8 million people in the U.S. contract infections each year from bacteria resistant to antibiotics, according to the U.S. Centers for Disease Control. More than 35,000 of them die.
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02.12.2024 | WHO updates list of medically important antibiotics for use in human medicine
CIDRAP | The World Health Organization (WHO) last week updated its list of medically important antimicrobials for use in human medicine, adding new categories based on their importance in human medicine, antimicrobial resistance (AMR) risk, and the potential human health implications of non-human use.
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02.08.2024 | Report warns of ‘brain drain’ from antibiotic research and development
CIDRAP | Two new reports this week from a coalition of industries working to combat antimicrobial resistance (AMR) highlight some of the progress that's been made, along with a critical problem that could undermine efforts to develop much-needed new antibiotics.
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02.07.2024 | Guidance on establishing national and local AMR surveillance systems in the Western Pacific Region
THE WORLD HEALTH ORGANIZATION | Antimicrobial resistance (AMR) is impacting our health, economies and development. Up to 5.2 million people may die because of resistant bacterial infections across the Western Pacific Region from 2020-2030.
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01.18.2024 | Trial supports switch to oral antibiotics in patients with low-risk Staph bloodstream infections
CIDRAP | The results of a randomized clinical trial show that early switch to oral antibiotic therapy was non-inferior to continuing intravenous (IV) therapy in patients with low-risk Staphylococcus aureus bloodstream infection, researchers reported yesterday in The Lancet Infectious Diseases.
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