INTEGRATED BIOTHERAPEUTICS   Rockville, MD, USA
integratedbiotherapeutics.com

IBT-V02
MULTI-VALENT TOXOID VACCINE

Direct-Acting Large Molecule Therapeutic; Vaccine
IBT-V02 is the novel vaccine that consists of five components representing toxoids for seven Staphylococcus Aureus (SA) toxins. Due to cross-reactivity, these toxoids elicit protective responses to 12-15 SA toxins. Efficacy of IBT- V02 components have been shown in various mouse and rabbit models of infection. This is the first entirely non-surface antigen-based vaccine for SA disease. The studies to be performed under CARB-X support will complete the pre-clinical development of IBT-V02 and transitions the program to phase I clinical trial.

Current Development Stage: Pre-Clinical

CARB-X Investment: Initial investment of up to $168k with potential option payments up to $12.8m. In August 2019, CARB-X awarded an additional $1.62m to IBT to develop a freeze-dried version of the vaccine for use in developing nations where cold-storage systems are not available.

Initial CARB-X Investment Date: October 1, 2017

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