CIDRAP | A new study in the Journal of the Pediatric Infectious Diseases Society describes what is believed to be the first case of bacterial meningitis caused by beta-lactamase–producing, ciprofloxacin-resistant Neisseria meningitidis in the United States. The case occurred in January 2020 in a previously healthy 5-month-old Maryland boy who was treated in the emergency department at Children’s National Hospital in Washington, DC. Although the boy was treated with broad-spectrum antibiotics and released after 7 days in the hospital, susceptibility testing of bacterial samples from the boy revealed resistance to five antibiotics—including penicillin and ciprofloxacin, which are typically used for treatment of people with confirmed N meningitidis infections and for prevention in those who’ve been in close contact with infected patients.