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CARB-X is accelerating global antibacterial innovation by investing in the development of new antibiotics and other life-saving products to combat the most dangerous drug-resistant bacteria. Our projects represent the world’s largest pre-clinical and early development pipeline of antibiotics and other therapeutics, diagnostics, microbiome, vaccines, and devices.

97.7+

$million

Invested

30+

company

Projects

6

different

Countries

11

new antibiotic classes in

Pipeline

The Challenge

Accelerate the development of novel antibiotics and other new approaches to address the emergence of drug-resistant superbugs.
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Spotlight on Science

SciBac is fighting fire with fire by using improved bugs as drugs

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“Antibiotics transformed modern medicine but overuse and inappropriate use have led to dangerous bacteria developing deadly resistance. Drug discovery must go hand-in-hand with concerted action to ensure antibiotics of last resort are reserved for patients where first-line treatments will not work. And we must ensure these treatments are available in all countries for those who need them.”

— Tim Jinks, Head of Drug Resistant Infections, Wellcome Trust
Watch this video with Tim Jinks on what Wellcome Trust is doing to address the rise of drug-resistant bacteria.

Funders

ASPR
BARDA
WellcomeTrust
NIAID
UK Government

Alliance Partners

Bill and Melinda Gates Foundation

Accelerators

Boston University
RTI
CLSI
MassBio
Broad Institute
DTRA
Wellcome Trust

Events

Events

01.17.19

, Belgium

ECRAID-Plan Kick-off meeting

01.29.19

,

REVIVE Webinar: Clinical development for non-developers Part 3: Antibacterial Drug Enhancer Combinations and Non-traditional Products

03.26.19

Bloomsbury, United Kingdom

The Economist Antimicrobial Resistance Summit - Preventing an Antibiotic Apocalypse

CARB-X News

  • 01.03.2019  |  CARB-X backs Forge to develop a new class of antibiotics to treat serious lung infections caused by Gram-negative bacteria, including multi-drug resistant P. aeruginosa full release

  • 09.24.2018  |  CARB-X calls for new ‘open science’ era in antibacterial innovation: Sharing scientific data will help speed the delivery of new antibiotics and other life-saving products to fight superbugs full release

  • 09.20.2018  |  CARB-X 2017-18 Annual Report is now online full release

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In The News

  • 12.10.2018  |  What’s holding pharma back from the next antibiotic breakthrough? full story

  • 12.03.2018  |  Therapy areas of the future full story

  • 11.30.2018  |  Antimicrobial resistance: The Ten Commandments – Two Years On – A Response full story

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