Carb-X

The Economist Antimicrobial Resistance Summit - Preventing an Antibiotic Apocalypse
2019-03-26 | BMA House Conference and Events Venue, Tavistock Square, Bloomsbury, London, WC1H 9JP, United Kingdom
Speakers include Kevin Outterson, CARB-X Executive Director.
Join 120+ health policy leaders, academics and other experts across the industry for a frank discussion to catalyse progress in bringing AMR under control, before it is too late. A series of expert panel discussions will dig into the topics that matter the most, using the convening power of The Economist brand to get the right people working together.

GARDP Webinar - Clinical development for non-developers Part 3: Antibacterial Drug Enhancer Combinations and Non-traditional Products
2019-03-28 17:00 - 18:30 (Europe/Paris) | Webinar
The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products. In this third webinar, we will discuss the development of antibacterial drug enhancer combinations and non-traditional products.
The webinar will be held from 5:00 pm – 6:30 pm CET / 12:00 pm – 13:30 pm EDT.
The presentations will be followed by a Q&A session.

REPAIR Impact Fund is open for investment proposals...
2019-04-01
…from European life science companies until May 10. Information about how to apply can be found at here.

The REPAIR Impact Fund is now open for investment proposals from European life science companies targeting AMR. Companies are invited to submit a non-confidential proposal, which will be evaluated during the spring. Successful projects will be invited to submit more extensive confidential proposals.

The window for submissions will be open until May 10th. Additional information and the proposal template can be found here.

This investment round is the second to European companies. Companies that took part in the first investment round without obtaining funding are very welcome to take part in this new round.

Annual ECCMID Meeting
2019-04-13 - 2019-04-16 | RAI Amsterdam, Europaplein, Amsterdam, NL 1078 GZ, Netherlands
ECCMID, as the world’s premier Clinical Microbiology & Infectious Diseases event, brings together experts from many fields to present their latest findings, guidelines and experiences to an audience of over 12,000 colleagues. This year, the Programme Committee has developed a multi-faceted program incorporating keynote lectures and oral sessions, as well as interactive workshops, meet-the-expert sessions, and a wide range of symposia.

19th World Vaccine Congress
2019-04-15 | Renaissance Washington DC Downtown Hotel, 999 9th St NW, Washington, DC, 20001, United States
Speakers include Dr. Barry Eisenstein, Chair of the CARB-X Advisory Board.
For the past 18 years, the World Vaccine Congress Washington congress has evolved and grown into the leading vaccines congress globally, with: 300 speakers, 1500 attendees and hundreds of networking opportunities. This year’s congress will feature a variety of pre-congress workshops and conferences in:

Cancer Immunotherapy
Immune Profiling
Respiratory Vaccines
Emerging & Re-emerging Diseases
Clinical Trials
Vaccine Partnerships
Bioprocessing & Manufacturing
Vaccines Safety
Logistics
Veterinary Vaccines

Throughout these sessions participants will learn how cutting-edge research efforts can be integrated with pharma, biotech, academia and government to produce more and better vaccines to the market.

ICOHAR, International Conference on One Health Antimicrobial Resistance
2019-04-16 - 2019-04-18 | Jaarbeusplein, Ulrecht, Netherlands
It is generally recognized that control and prevention of antimicrobial resistance (AMR) requires a holistic One Health approach involving specialists from different sectors. In line with this concept, the 2nd ICOHAR aims to bring together representatives from all relevant sectors (e.g. public health, human and veterinary medicine, livestock production, food safety and environmental sciences) to share research and education strategies for understanding and reducing the risks of AMR at the interphase between humans, animals and the environment. The programme does not only focus on zoonotic transfer of AMR but also on the numerous AMR-related challenges shared by clinicians, clinical microbiologists, infectious disease specialists and researchers working in these sectors.
To view the program, please click here.

Annual SHEA (Soc. for Hospital Epidemiology of America) Spring meeting
2019-04-24 - 2019-04-26 | Westin Boston Waterfront, 425 Summer St, Boston, MA, 02210, United States
This conference is designed for physicians, infection preventionists, healthcare epidemiologists, infectious disease specialists, microbiologists, nurses, pharmacists, and other healthcare professionals interested in healthcare epidemiology, infection prevention, Antimicrobial Stewardship, surveillance, research methods, patient safety, environmental issues, and quality improvement.
The SHEA 2019 Program Committee combines the expertise of SHEA members who have served on SHEA meeting planning committees for many years and active leaders from the SHEA Education Committee. It also includes broad subject matter expertise in healthcare epidemiology, antibiotic stewardship, long-term care, research methods, clinical microbiology, patient safety and quality, implementation science, and a wide range of opportunities for networking and communication with peers and experts in the field.
To view the agenda, please click here.

National Academy of Sciences 155th Annual Meeting
2019-04-28 - 2019-05-01 | National Academy of Sciences, 2101 Constitution Ave., N.W., Washington, DC, United States
Advising the Nation. Advancing the Discussion. Connecting New Frontiers.
Society is facing an array of complex policy questions. The National Academies of Sciences, Engineering, and Medicine provides nonpartisan, objective guidance for decision makers on pressing issues. and marshals the energy and intellect of the nation’s critical thinkers to respond to policy challenges with science, engineering, and medicine at their core.
Through a meticulous process of information collection, evidence analysis, and deliberation, NAS studies provide blueprints for progress. By shining a spotlight on subjects and facilitating dialogue across disciplines, their work advances understanding of critical issues.
For information on live webcasts, click here.
For information on the agenda click here.
Visit the NAS website here.

37th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID)
2019-05-06 - 2019-05-11 | Ljubljana, Slovenia
The 37​th Annual Meeting of the European Society for Paediatric Infectious Diseases will feature a wide range of sessions and learning opportunities showcasing the latest research and developments in the field hosted by leading international experts. The meeting aims to bring together the most prominent researchers in the field of paediatric infectious diseases, immunology and epidemiology and to fill in the gaps between these disciplines in a relaxed, smart albeit casual atmosphere.

Live Webinar: CARB-X 2019 Funding Rounds
2019-05-16 09:00 - 10:00 (America/New_York) | Webinar, 765 Commonwealth Avenue, Boston, MA, 02215, United States
Kevin Outterson, CARB-X Executive Director, and Karen Gallant, CARB-X Global R&D Project Director, present details of CARB-X’s four new funding rounds announced April 30, 2019, and answer questions during this webinar. To attend the live webinar, please register by clicking the link below. A recording of the webinar will be available for viewing shortly after the event. The recording will be available on the CARB-X website in the Apply > What CARB-X funds section.
Please click here to register.

GARDP Mining Chemical Libraries for New Antibacterials
2019-05-21 17:00 - 18:30 (Europe/Helsinki) | Webinar, 765 Commonwealth Avenue, Boston, MA, 02215, United States
Despite the promise of target-based drug discovery ushered in by the genomics era, no mechanistically novel rationally designed antibiotic has reached clinically utility to address the threat of multi-drug resistant bacterial pathogens. Phenotypic screening remains the primary source for new antibacterial compounds, which mainly come from mining various chemical libraries. In this webinar, Carl Balibar (Merck Research Laboratories) will discuss screen design, target bias, and hit-prioritization strategies to identify those entities with the greatest opportunity to be developed into the next new antibiotic.
The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products. In this third webinar, we will discuss the development of antibacterial drug enhancer combinations and non-traditional products.
Please note, this webinar has been rescheduled from April 4th to May 21st, 2019.
The webinar will be held from 5:00 pm – 6:30 pm CEST / 11:00 pm – 12:30 pm EDT.
The presentation will be followed by a Q&A session.
Register here for this live webinar.

Global AMR R&D Hub “Increasing Investments for AMR R&D” Workshop
2019-05-28 | Domaine de Penthes, Chemin de l'Impératrice 18, Pregny-Chambésy, 1292, Switzerland
Participants include Kevin Outterson, Executive Director of CARB-X.
The Global AMR R&D Hub is pleased to announce a one-day workshop on “Increasing Investments
for AMR R&D”, which will take place on Tuesday May 28 2019 in Geneva, Switzerland. The event
will gather representatives from governments, funders, industry, investors and other stakeholders
interested in the field of antimicrobial resistance.
Antimicrobial resistance (AMR) represents an urgent major global health threat. Currently, there is
an insufficient number of treatments and tools in the AMR research and development (R&D)
pipeline to tackle this issue. Building on ongoing initiatives, increasing investments across the One
Health spectrum is required. In particular, more effort is needed in the animal and plant fields as
well as applicability in low- and middle-income countries (LMIC).
This workshop aims to discuss investments and financing mechanisms for AMR R&D and provide
recommendations for funders and investors on how to address the vital issue of increasing
investments in AMR R&D in a One Health context that also considers applicability in LMIC.
Please click here to learn more.

CARB-X Presentation: 2019 Funding Rounds
2019-05-31 10:00 - 11:45 (America/New_York) | North Carolina Biotechnology Center, 15 T.W. Alexander Drive, Research Triangle Park, NC, 27709-3547, United States
Presentation by Karen Gallant, CARB-X Acting R&D Chief/Deputy Director. Attendees include Richard Alm, CARB-X Alliance Director.
Please join NCBiotech and RTI International as we host CARB-X Global R&D Project Director Karen Gallant for an informational session about CARB-X and the upcoming funding rounds. Karen will provide an overview of the CARB-X initiative and leave plenty of time to get all questions answered. This event is FREE to attend.
For further information, please refer to the CARB-X press release and website.

Agenda
10:00 a.m. – Presentation by Karen Gallant, Global R&D Project Director, CARB-X
10:30 a.m. – Presentation: RTI International as a CARB-X Accelerator
10:45 a.m. – Q&A Session
11:15 a.m. – Networking
11:45 a.m. – Adjourn

Registration
There is some availability for a few companies to have one-on-one meetings with CARB-X. If you are interested, please select that option on the registration page.

2019 BIO International Convention
2019-06-03 - 2019-06-06 | Philadelphia Convention Center, 1101 Arch Street, Philadelphia, PA, 19107, United States
The BIO International Convention (BIO) attracts 16,000+ biotechnology and pharma leaders who come together for one week of intensive networking to discover new opportunities and promising partnerships. BIO brings together a wide spectrum of life science and application areas including drug discovery, biomanufacturing, genomics, biofuels, nanotechnology and cell therapy.
The key benefits of attending the 2019 BIO International Convention are access to global biotech and pharma leaders via BIO One-on-One Partnering, exposure to industry thought-leaders with over 500 education sessions at your fingertips, and unparalleled networking opportunities with 16,000+ attendees from 67 countries.
See the schedule here.

Live Webinar: GARDP/REVIVE Mining Chemical Libraries for New Antibacterials - Session 2
2019-06-04 13:30 - 15:00 (Europe/Berlin) | Boston University School of Law, 765 Commonwealth Avenue, Boston, MA, 02215, United States
The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products.
In this webinar the recording of Carl Balibar’s presentation ‘Mining of chemical libraries for new antibacterials’ (original webinar on 21 May) will be followed by another live Q&A session with Carl.
Despite the promise of target-based drug discovery ushered in by the genomics era, no mechanistically novel rationally designed antibiotic has reached clinically utility to address the threat of multi-drug resistant bacterial pathogens. Phenotypic screening remains the primary source for new antibacterial compounds, which mainly come from mining various chemical libraries. In this webinar, Carl Balibar (Merck Research Laboratories) will discuss screen design, target bias, and hit-prioritization strategies to identify those entities with the greatest opportunity to be developed into the next new antibiotic.
Speakers:
Carl Balibar, Principal Scientist, Merck Research Laboratories
Moderator:
Benjamin Blasco, Discovery Senior Project Manager, GARDP
Register here for this live webinar.

Medical, Biomedical & Biodefense: Support to the Warfighter Symposium
2019-06-05 - 2019-06-06 | The Friday Conference Center, 100 Friday Center Drive, Chapel Hill, NC, 27599, United States
Panelists members include Kevin Outterson, Executive Director of CARB-X, on the “Public-Private Partnerships: Research and Development Consortia and Accelerators” panel.

This panel will discuss the use of public-private partnerships as models for stimulating innovation through sponsored research and development. The panelists will provide overviews of several partnership-enabled consortia and accelerators, including BARDA’s new Division of Research, Innovation, and Ventures and their participation in the partnership, Combating Antibiotic Resistant Bacteria, and, as well as DoD’s Medical CBRN Defense Consortium and Medical Technology Enterprise Consortium. Presenters will discuss their organization’s background and structure, as well as their unique mechanisms for engaging the research community to solve significant public health and biomedical challenges.

The Symposium will focus on two separate tracts. The first, “Medical Support to the Warfighter,” will connect businesses and university researchers with military and other federal agencies that require or purchase medical supplies, equipment, devices, pharmaceuticals, information technology and services, or fund medical-related research and development.
The second tract, “Biomedical and Biodefense Support to the Warfighter,” will focus on establishing dialogue between industry and academia-based technology innovators and military and government officials to address the future biomedical and biodefense needs of the military and our nation.

To learn more, please click here.

Live Webinar: Funding Opportunities for Antimicrobial Drug Development from the Cystic Fibrosis Foundation
2019-06-11 10:00 - 11:00 (America/New_York) | Boston University School of Law, 765 Commonwealth Avenue, Boston, MA, 02215, United States
Interested in new funding opportunities for infection drug development?
The Cystic Fibrosis Foundation (CFF) has teamed up with CARB-X to host a live webinar on June 11, from 10:00am – 11:00am ET, to introduce their new Infection Research Initiative.
During the webinar, Dr. Ann Field, Senior Director of Drug Discovery and Development at the Cystic Fibrosis Foundation, will discuss potential funding opportunities for therapeutic development of anti-infectives in key organisms of interest for CF infections. The presentation will be followed by an interactive Q&A session.
Webinar Summary
Learn about funding opportunities for infection drug development through the Cystic Fibrosis Foundation. This webinar will include:

Overview of the CF Foundation and the recently announced Infection Research Initiative
CF Foundation interest in supporting therapeutic development for anti-infectives in key organisms of interest for CF infections
Therapeutic Development Award Process and collaboration opportunities

To join this webinar, please register here.
If you have questions or comments, please let us know. Feel free to email your questions or comments to Raj Shetty at dshetty@carbx.org before the webinar, or save them for the live Q&A session following the presentation. We look forward to hearing from you!

Live Webinar: GARDP/REVIVE Models for antimicrobial R&D: Development and use of in vivo models for infectious disease research
2019-06-11 17:00 - 18:30 (Europe/Berlin) | Boston University School of Law, 765 Commonwealth Avenue, Boston, MA, 02215, United States
The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products.
In this webinar, William J. Weiss, Director, PreClinical Services, University of North Texas System College of Pharmacy, will introduce experimental design of animal models for antimicrobial research. He will discuss questions such as 1) Where to start and what model to use? 2) Are animal models of bacterial infection reflective of the clinical condition? 3) Are in vivo animal model results predictive of clinical efficacy? The presentation will be followed by a Q&A session moderated by Peter Warn, Senior Vice President, Anti-infective Discovery, Evotec.
Speakers:
William J. Weiss, Director, PreClinical Services, University of North Texas System College of Pharmacy
Moderator:
Peter Warn, Senior Vice President, Anti-infective Discovery, Evotec
Register here for this live webinar.

ASM Microbe 2019
2019-06-20 - 2019-06-24 | Moscone Center, 747 Howard Street, San Francisco, CA, 94103, United States
Each day at ASM Microbe 2019 offers you the chance to delve into your scientific interest and specialties, discover cutting-edge research in the poster and oral presentations, and connect with a world of microbiology experts. View the ASM Microbe 2019 Schedule at a Glance for a preliminary peek at what is in store for you.

ASM Microbe Breakout Session - Enabling Academia to Fill the Discovery Gap
2019-06-24 07:15 - 08:15 (America/Los_Angeles) | Moscone Center, 747 Howard Street, San Francisco, CA, 94103, United States
Presentations developed in cooperation with GARDP, CARB-X, and REPAIR Impact Fund.
Antimicrobial resistance (AMR) continues to be a major problem that is not being addressed adequately by the pharmaceutical industry. Academic research is more frequently serving as a source for novel antimicrobial agents to treat infections caused by antibiotic-resistant organisms. In this session, drug discovery efforts originating from academic laboratories will be discussed. The importance of collaborative efforts will be emphasized.

International Council of Academies of Engineering and Technological Sciences (CAETS) Conference
2019-06-25 - 2019-06-28 | Stockholm, Stockholm, Sweden
Speakers include Kevin Outterson, Executive Director of CARB-X.
The Royal Swedish Academy of Engineering Sciences (IVA) is hosting the yearly conference for the International Council of Academies of Engineering and Technological Sciences (CAETS) in 2019. CAETS in a independent non-political, non-governmental international organization of engineering and technological science academies worldwide. The conference will focus on what engineering and technological science has accomplished in the last 100 years as well as future challenges, focusing on the topics of Health, Energy, Affordable Living, Superintelligens and Distrubution of Resources. The conference will focus on how engineering and technological science can morph into the future and contribute to solutions.

Live Webinar: GARDP/REVIVE - Find out how GARDP is redoubling its efforts to accelerate the development and delivery of new and improved antibiotics
2019-06-26 10:30 - 11:30 (America/New_York) | Boston University School of Law, 765 Commonwealth Avenue, Boston, MA, 02215, United States
In this webinar, Dr Manica Balasegaram, GARDP’s Executive Director will highlight GARDP’s role in accelerating the implementation of WHO’s Global Action Plan, and share GARDP’s updated strategy. Following his presentation, you will have the opportunity to ask questions in a Q&A session moderated by Jennifer Katz, GARDP’s Director of External Affairs.
Register here for this live webinar.

Institut Pasteur Financing Start-Ups in Life Sciences Workshop
2019-07-05
Additional Details Forthcoming.

Live Webinar: GARDP/REVIVE Infection models for antimicrobial R&D: Intracellular models
2019-07-09 11:00 - 12:30 (America/New_York) | Boston University School of Law, 765 Commonwealth Avenue, Boston, MA, 02215, United States
The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products.
In this webinar, Françoise van Bambeke, Research Director Cellular and Molecular Pharmacology, Louvain Drug Research Institute, Catholic University of Louvain (FR), will talk about intracellular activity of antibiotics. Topics discussed will include:

The role of intracellular survival in chronic infections and its contribution to poor response to antibiotics
In vitro models to study intracellular activity of antibiotics
Cellular pharmacokinetic (PK) parameters predictive of intracellular potency for antibiotics
Cellular pharmacodynamics (PD) parameters predictive of intracellular efficacy for antibiotics

The presentation will be followed by a Q&A session
Speakers:
Françoise van Bambeke, Research Director Cellular and Molecular Pharmacology, Louvain Drug Research Institute, Catholic University of Louvain (FR)
Moderator:
Laura Piddock, Director of Scientific Affairs, GARDP
Register here for this live webinar.

Deadline to submit updates to the World Health Organization clinical antibacterial pipeline
2019-07-22 08:00 - 17:00 (America/New_York) | CARB-X, 765 Commonwealth Ave, Boston, MA, 02215, United States
Please share any pipeline additions and changes that you are aware of by 22 July 2019. Download and use this form to provide updates. The latest pipeline update (as of July 1, 2018), can be found as a manuscript (Theuretzbacher et al. Lancet ID 2018), and as a set of summary tables. Contact Sarah Paulin (paulins@who.int).

The Role of NIH in Drug Development Innovation and its Impact on Patient Access: A workshop
2019-07-24 - 2019-07-25 | The National Academies Keck Building, 500 5th Street NW, Washington, DC, 20001, United States
This is an open session hosted by the National Academy of Sciences, Engineering, and Medicine. The 1.5-day public workshop to will be held on July 24-25, 2019 in Washington, D.C and focus on the translation of federal investments in biomedical science to innovation in drug development and how the public benefits from that investment in terms of drug pricing and access. The meeting will feature invited presentations and panel discussions on topics that may include:

how federal funding for biomedical research, particularly via NIH, has contributed to new drug development, both directly and indirectly
the pricing of drugs that have benefited from federal investments in biomedical science;
the role of technology and patent transfer to and from entrepreneurial organizations associated with NIH-funded research
potential ways to better track, quantify, and document NIH contributions to innovation in drug development
potential strategies and policies to facilitate the translation of federally-funded biomedical research into innovations in drug development and to help ensure that the public has affordable access to those innovative medicines.
The planning committee will develop the agenda, select and invite subject matter experts and discussants, and moderate the discussions. A proceedings of the event will be prepared in accordance with institutional guidelines.

To learn more, click here.

UK Medical Research Council National PhD Training Programme in AMR - Annual Conference
2019-08-12 08:00 - 2019-08-13 17:00 (America/New_York) | University of Bristol, Bristol, BS8 1TD, United Kingdom
Keynote lecture given by Kevin Outterson, Executive Director of CARB-X.
Additional details forthcoming.

Live Webinar: GARDP/REVIVE - Models for antimicrobial R&D: Computational modelling for population PK and PKPD
2019-08-20 11:00 - 12:30 (America/New_York) | Webinar, 765 Commonwealth Avenue, Boston, MA, 02215, United States
The overall goal of this series of webinars is to provide, for the non-clinical developer, an understanding of the risks of development for various kinds of antibacterial products.
In this webinar, Lena Friberg and Elisabet Nielsen (Department of Pharmaceutical Biosciences, Uppsala University, Sweden), will discuss:

Population PK modelling to characterize drug exposure and variability
PKPD-modelling to characterize preclinical time-kill data
PKPD-modelling for translation to patients
Model-based dose-individualization

The presentation will be followed by a Q&A session.

Speakers:
Lena Friberg and Elisabet Nielsen, Department of Pharmaceutical Biosciences, Uppsala University, Sweden
Moderator:
Ursula Theuretzbacher, Center for Anti-Infective Agents, Vienna, Austria
Register here for this live webinar.

Annual ASM/ESCMID Conference on Antibiotic Development to Meet the Challenge of AMR
2019-09-03 - 2019-09-06 | Boston, Venue Forthcoming, Boston, MA, United States
The ASM/ECSMID Conference on Drug Development returns to Boston, Massachusetts for 2019. Check back soon for program details.
Antimicrobial drug resistance (AMR) is an urgent global health problem. New antimicrobial drug development is increasingly viewed as a priority by National and International bodies. There are relatively few agents in developmental pipelines and a paucity of identified microbiological targets that can be exploited for drug development. Co-sponsored by the American Society for Microbiology (ASM) and the European Society for Clinical Microbiology and Infectious Diseases (ESCMID), this multidisciplinary meeting will address the challenges, opportunities and current requirements for antimicrobial drug development for AMR.

Harvard Museum of Natural History Reception and Mixer
2019-09-04 18:30 - 21:00 (America/New_York) | Harvard Campus, 52 Oxford Street, Cambridge, MA, 02138, United States
Sponsored by the Harvard Microbial Sciences Initiative and the Boston Area Antimicrobial Research Network

Drinks, hors d’oeuvres, and exclusive private access to the Harvard Museum of Natural History https://hmnh.harvard.edu/. This is a chance to unwind with fellow attendees at the ASM/ESCMID Conference on Drug Development to Meet the Challenge of Antimicrobial Resistance, and meet those from the Harvard University Microbial Sciences Initiative and Boston Area Antimicrobial Resistance Network sharing that interest. The museum is the quintessential university natural history museum with many unique and historical collections and displays, located on the main Cambridge campus of Harvard University.
SPACE IS LIMITED to the first 150 to RSVP.
To reserve your place – reply to: michael_gilmore@meei.harvard.edu. Copy the subject line I WILL ATTEND, and provide your name, affiliation and email. You will be provided a map, directions and an ENTRY TICKET in response.
