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November 2019

CRISPR and Gene Editing: The New Frontier in Fighting Infectious Diseases?

November 12, 2019 @ 4:00 pm - 7:00 pm
JLabs @ Toronto, 661 University Ave Suite 1300
Toronto, Ontario Canada
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Presenters include Karen Gallant, Deputy Executive Director of CARB-X. Few technologies have the potential to disrupt and eliminate infectious disease and viral infections– but gene editing, CRISPR in particular, is a latent technology that could change biotech – and we’re just seeing the beginning of what effect it could have on the world. With scientific promise comes interest from investors – a surge of biotech startups are utilizing CRISPR technology for many different applications such as at-home testing, in-clinic uses,…

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The 2019 Canada Gairdner Foundation / Ontario International Symposium: Fuelling the Fight against AMR – Global Innovations in Research & Discovery

November 14, 2019 - November 15, 2019
McMaster University, 1280 Main Street W
Hamilton, Ontario L8S 4L8 Canada
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Kevin Outterson, Executive Director of CARB-X, is participating in a special panel discussion titled "When antibiotics fail: An international conversation about the worrisome evidence of impact and what can be done". During this session, a panel of international experts will discuss the findings from a new report by the Council of Canadian Academies and discuss what steps can be taken to reduce the impact of rising resistance rates around the world.  Additional panelists include Prof. Andrew Morris, Prof. Dame Sally…

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FDA Workshop: Enhancing the Clinical Trial Enterprise for Antibacterial Drug Development in the United States

November 18, 2019 - November 19, 2019
FDA White Oak Campus – Building 31, 10903 New Hampshire Ave
Silver Spring, MD 20993 United States
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Presenters include Kevin Outterson, Executive Director of CARB-X, and Erin Duffy, CARB-X Chief of Research and Development. The FDA, IDSA, NIAID and Pew are co-sponsoring this workshop to focus on Enhancing the Clinical Trial Enterprise for Antibacterial Drug Development in the United States. This workshop will bring together a diverse array of subject matter experts in the fields of infectious diseases (ID), academics and industry and other government bodies to better understand the current state of U.S. based ID trials…

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Live Webinar: GARDP/REVIVE – Innovation in point-of-care diagnostics for sepsis and bloodstream infections

November 26, 2019 @ 3:30 am - 5:00 am
Webinar, 765 Commonwealth Avenue
Boston, MA 02215 United States
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In this webinar our moderator Caroline Purslow (Nesta Challenges) will welcome three speakers. Till Bachmann (University of Edinburgh) will give an overview of recent advances in AMR diagnostics development. He will discuss: State of the art approaches for diagnosing infections and AMR Pipeline of promising tests Challenges of adoption Amrita Sukrity (SpotSense) will draw from her experience as a founder of SpotSense and talk about diagnosis of neonatal sepsis at the community level. Topics discussed will include: Challenges across diagnosing…

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January 2020

Exploring Opportunities to Reform Antimicrobial Payment and Post-Market Incentives

January 16 @ 10:30 am - 4:30 pm
Washington Marriott at Metro Center, 775 12th Street NW
Washington, DC 20005 United States
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Speakers include Kevin Outterson, Executive Director of CARB-X. The rise of antimicrobial resistance and the corresponding lack of novel antibiotic development impacts the ability of physicians to provide appropriate care for patients. The greatest barriers to a robust antibiotic ecosystem are low return on investment (ROI) and limited market opportunities, in part due to payment decisions that don’t reflect the value of antibiotics that extends beyond the hospital stay. For years, policy makers and other stakeholders have been exploring ways…

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Davos 2020 World Economic Forum – Novo Nordisk Foundation and Novo Holdings: The Broken Model of Antimicrobial resistance

January 21 @ 8:00 am - 5:00 pm
DAVOS-KLOSTERS Switzerland + Google Map

Moderator: Kevin Outterson, Executive Director, CARB-X, Professor of Law, Boston University Panel: Lars Rebien Sorensen, Chairman of the Novo Nordisk Foundation and Novo Holdings Jeremy Farrar, Director, Wellcome Trust Dr. Malin Grape, Head of Antibiotics Unit, The Public Health Agency of Sweden Thomas Cueni, Director General, IFPMA Jayasree K. Iyer, Executive Director, Access to Medicine Foundation Francesca Colombo, Head of the Health Division, OECD Antimicrobial resistance is one of the biggest threats to human health. The Novo Nordisk Foundation is hosting…

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Live Webinar: GARDP/REVIVE – Testing for the potential of emergence of antimicrobial resistance

January 21 @ 11:00 am - 12:30 pm

In this webinar, the following aspects will be presented: What are the most common techniques used to measure the extent of the risk of selecting for resistance when using a novel direct-acting antibacterial. What are the advantages and limitations of these techniques? What are some techniques that may be used to understand the origins of resistance selection? How to rationalize/manage the risk of translation of the resistance selection from in vitro to the clinical settings? The presentation will be followed…

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February 2020

Live Webinar: GARDP/REVIVE – Non-traditional antibacterial therapeutic options and challenges

February 4 @ 11:00 am - 12:30 pm
Webinar, 765 Commonwealth Avenue
Boston, MA 02215 United States
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In this webinar, the following aspects will be presented: Discovery and early development of “non-traditional” antibacterial approaches is a noticeable trend in the pre-clinical global pipeline These approaches include anti-virulence strategies, microbiome-modifying therapies, phages and others such as nanoparticles, immunotherapy and drug-resistance modulation Some of these approaches require novel preclinical efficacy models to predict clinical outcome Pathogen-specific or even patient-specific strategies dominate this field A major challenge will be to show efficacy in clinical trials The presentation will be followed…

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Live Webinar: GARDP/REVIVE – PK/PD murine infection models: Focus on study elements, variability, and interpretation of results

February 27 @ 11:00 am - 12:30 pm
Webinar, 765 Commonwealth Avenue
Boston, MA 02215 United States
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In this webinar, Alexander J. Lepak will review critical study elements that lead to robust preclinical PK/PD results in the murine model. Topics discussed will include: Understanding and embracing the inherent variability in many components of the murine model Demonstrating how to generate and interpret preclinical murine model PK/PD results The presentation will be followed by a Q&A session. The material presented in this webinar was shown but not recorded at the ASM/ESCMID Conference on Drug Development to Meet the…

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March 2020

BAARN2020: Boston Area Antimicrobial Research Network Meeting

March 20 @ 9:00 am - 5:00 pm
Harvard Campus, 52 Oxford Street
Cambridge, MA 02138 United States
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The Boston Area Antimicrobial Resistance Network Meeting, to be held on Friday, March 20th. BAARN2020 will be the 7th iteration of this flagship MSI event, bringing together our collective talents across academia and industry to address the persistent dilemma posed by antimicrobial resistant infection.   Talks will begin at 9 AM in the Northwest Labs Building at 52 Oxford Street, Cambridge MA 02138, and our sessions will conclude with the annual Stuart Levy Lecture. A reception will follow at 6…

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