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Apply Here

The second of three funding cycle periods is open for Expression of Interest submissions. Applicants can register in the CARB-X Portal by clicking the button below to begin.

Please click here for technical guidance on the CARB-X Portal. If you need technical assistance, please contact

Expressions of Interest (EOI) for all three themes may be submitted during the following timeframes:

  • October 17 at 09:00 ET to October 31, 2022 at 23:59 ET
  • January 16 at 09:00 ET to January 30, 2023 at 23:59 ET
  • April 17 at 09:00 ET to May 1, 2023 at 23:59 ET

The EOI includes three sections:

Organization Details requests details about the legal structure and size of your organization.

Project/Product Details requests details about your project/product including:

  • Type of product (i.e. therapeutic, preventative or diagnostic)
  • Name of your project
  • Target pathogen(s) and whether your product covers isolates resistant to antibiotics from certain classes
  • Primary indication/clinical indication and any secondary indications/clinical applications
  • Stage of development
  • Intended route of administration
  • For Therapeutics/ Preventatives: Modality, Chemical class, Mechanism of action, Details about the target, Target novelty
  • For Diagnostics: Level of complexity, Result output, Diagnostic technology type, Sample type, Time-to-result, Sensitivity/specificity, Target average sales price

You will be asked to describe your therapeutic/preventative/diagnostic in 5000 characters or fewer:

Your application will be judged on the merits of its scientific content; describe your science with as much data as possible. Please do provide sufficient data to allow a knowledgeable scientist to get a reasonable sense of the therapeutic/preventative/ diagnostic. Do not provide other manuscripts, references, citations or similar. Note that the form can only accept text; you may not enter tables or graphics. Do not include foundational information regarding the significance of antibiotic resistance; this is not necessary, as the reviewers understand this.

Project Costs requests details about how much funding you are requesting from CARB-X.

You will be asked to respond to the following question in 250 characters or fewer: Please describe where you are in your project and where you want to progress to. How much funding do you need from CARB-X to complete this scope of work (in USD)?

Target-product profiles can be found here and minimal acceptable criteria can be found here.